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Clinical Case: Is this just ‘old age’?

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Student Surgery: You’re  a medical student conducting a surgery list under supervision from your GP trainer. Your next patient is a retired GP who has been booked in by his wife for concerns about his memory.

A 74 year old retired GP, Dr Wallis comes to see you.His wife reports that his memory is not ‘as it was’  however the retired GP dismisses this as ‘nonsense’ and proceeds to tell you about his early research on the use of anti tuberculous medications. His wife is concerned that he may have a brain tumour. The concern about this is that she has read brain tumours can cause memory problems.

Dr Wallis is frustrated by his wife’s concerns about his memory and mentions she is always meddling in his affairs. In his history his wife tells you he has put on a stone in weight, and fractured an ankle when being run over by a car 12 months ago.

PMHx

Previous history of skin psoriasis, treated with topical preparations only.

Drug history

Vitamin D tablets ordered over the internet (patient unsure of strength, wife believes it to be 1000 international units a day)

Examination

You proceed to examine Dr Wallis to evaluate him for any neurological problems. The examination is as follows.

Observations normal. Normal Cardiovascular, Respiratory and Gastrointestinal Examination

Neurology:



Upper Limbs

Lower Limbs

Right Left
Right Left
Tone N N N N
Power


5/5 5/5 5/5 5/5
Coordination N N N N
Sensation

Fine touch

Proprioception

N

N

N

N

N

N

N

N

Reflexes

Biceps

triceps

supinator


+

+

-

+

+

+

Knee

Ankle

Plantar

+

-

?

+

+

?

Cranial Nerve Exam

Normal. Fundoscopy normal.

Mental Test Score:

Question Mark (x/10)
Age Correct
DOB

Correct

Time (nearest Hr)

Correct

Person

Correct

Place (house number/ name of hospital)

Incorrect

Recall Address

Correct

WWII

Incorrect

Year

Correct

Queen

Correct

20-1

Correct

Adapted from Hodkinson HM. “Evaluation of a mental test score for assessment of mental impairment in the elderly.” Age and Ageing 1972;1:233-8

Recent blood tests

Test Result Normal Range
Hb 12.9 (12-15g/dl)
WCC 5.4 (4-10 x109/l)
Plt 152 (150-300 x109/l)
MCV 88 (80-99 fL)
INR 0.9 (0.9-1.3)
Na 137 (135-145 mmol/l)
K 4.8 (3.5-5.1mmol/l)
U 4.1 (4-9mmol/l)
Creatinine 88 (60-100 micromols/l)
Albumin 39 (35-45g/l)
Alk Phos 53 (<110iu/l)
ALT 45 (<40 iu/l)
Bilirubin 19 (<20 micromols/l)
CRP 9 <5
TSH 5.6 (0.5-5)
Fasting Blood sugar 6.2 (<7mmol/l)

What is the most likely diagnosis is this just ‘old age’, and does the patient require any other investigations? You can pick a maximum of 5 answers.

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